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Dissolution Cannula
The administration of drugs via oral dosage forms is one of the most common and effective means of delivering treatments to patients. When a dosage form is swallowed, the rate at which it releases the active ingredient is critical to ensure that the drug is delivered properly. The rate at which the drug is released is called the dissolution rate.
In fact, all drug forms have a dissolution rate. Creams, skin patches and implants and others, all release their drugs so they can be taken up by the body.
One of the problems facing pharmaceutical manufacturers is to how optimise the amount of drug available to the body, i.e. itsbioavailability. Inadequacies in bioavailability can mean that the treatment is ineffective and at worst potentially dangerous (toxic overdose). All kinds of factors affect this from the formulation of the dosage form, size, shape, excipients, bindings and other physical characteristics, to the pH, temperature and so on.
The actual drug release in the human body can be measuredin-vivoby measuring the plasma or urine concentrations in the patient. However, there are certain obvious impracticalities involved in employing such techniques on a routine basis. These difficulties have led to the introduction of officialin-vitrotests which are now rigorously and comprehensively defined in the respective Pharmacopoeia and recent harmonisation between the various Pharmacopoeia (notably the USP, BP, EP and JP) has lead to global standardisation in the measurement of drug release rates
Dissolution Cannula Bend Type
Product Price: Rs 175 / picGet Best Price
Minimum Order Quantity: 100 pic
Product Brochure
Product Details:
| Usage/Application | Sampling Cannulae are used to take samples from the dissolution tes |
| Brand | A One |
| Material | Stainless Steel & PP |
| Shape | Round |
| Size | for 900 ml jar |
| Country of Origin | Made in India |
| Material Grade | SS 304 |
| Packaging Type | Box |
Sampling Cannula are used to take samples from the dissolution test. Choice of cannula is important as the sampling method must not adversely affect the accuracy of the dissolution test and cause erroneous results.
Key Considerations:
· Sampling Position - this is important as there can be a concentration of the solution may vary according to the sampling position. The sample should be taken midway between the top of the stirring element and at least 10mm away from the side of the vessel.
· Cannula Length - cannula vary in length from 4.75” (120mm) to 15” (380mm). There are different lengths for 500ml and 900ml tests as the midpoint will change with the volume. Extended lengths are normally used for “through the head sampling” whereby the cannula passes through the drive head of the dissolution bath.
· Cannula Material - The cannula are made from either stainless steel so that they do not adsorb or interfere with the active ingredient
· Stoppers - cannula can be used with stoppers during manual sampling to ensure that the sample is always taken from the same depth.
manufactured to ISO9001 quality standards.
Additional Information:
- Item Code: SCB900
- Production Capacity: 10000
- Delivery Time: 4-5 days
- Packaging Details: BOX
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Dissolution Sampling Cannulas
Product Price: Rs 250 / PieceGet Best Price
Minimum Order Quantity: 10 Piece
Product Brochure
Product Details:
| Size | Standard |
| Usage/Application | Laboratory |
| Material | Ss316 |
| Is It Sterilized | Non Sterilized |
| Automation Grade | Manual |
| Packaging Type | Corrugated |
| Product Type | PTFE Stopper |
| Quantity Per Pack | Pkt /10 pic |
| Flow Rate | 10 ml/ minute |
| Is It Portable | Non Portable |
| Is It Reusable | Reusable |
| Brand | Aone |
| Country of Origin | Made in India |
Sampling Cannula are used to take samples from the dissolution test. Choice of cannula is important as the sampling method must not adversely affect the accuracy of the dissolution test and cause erroneous results.
Key Considerations:
· Sampling Position - this is important as there can be a concentration of the solution may vary according to the sampling position. The sample should be taken midway between the top of the stirring element and at least 10mm away from the side of the vessel.
· Cannula Length - cannula vary in length from 4.75” (120mm) to 15” (380mm). There are different lengths for 500ml and 900ml tests as the midpoint will change with the volume. Extended lengths are normally used for “through the head sampling” whereby the cannula passes through the drive head of the dissolution bath.
· Cannula Material - The cannula are made from either stainless steel so that they do not adsorb or interfere with the active ingredient
· Stoppers - cannula can be used with stoppers during manual sampling to ensure that the sample is always taken from the same depth.
manufactured to ISO9001 quality standards.
Additional Information:
- Item Code: SC_T900
- Production Capacity: 5000
- Delivery Time: 1 week
- Packaging Details: Box
Get Best QuoteRequest A Callback